Biphenyl

Biphenyl

SCHEMBL8941755

COc1cc(C)ccc1OP(=O)(O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
HPGD P15428 4/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
INPPL1 O15357 1/20 0.44
INPP5A Q14642 1/20 0.44
L3MBTL1 Q9Y468 4/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 4/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 1/20 0.43
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HSP90AA1 P07900 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ACLY P53396 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14403284 0.91 ACHE (0.61) ACHEHPGDCYP1A2CYP3A4CYP2C9
SCHEMBL5518516 0.81 PTGDR2 (0.57) HPGDINPPL1INPP5AL3MBTL1KDM4E
SCHEMBL8941757 0.77 ACHE (0.52) ACHEHPGDCYP1A2CYP3A4CYP2C9
SCHEMBL28677915 0.77 KMT2A (0.46) HPGDKDM4EMAPTHTTSMN1; SMN2
SCHEMBL19808 0.76 INPPL1 (0.57) HPGDCYP1A2CYP3A4CYP2C19INPPL1
SCHEMBL30770359 0.76 INPPL1 (0.57) HPGDCYP1A2CYP3A4CYP2C19INPPL1
SCHEMBL11740599 0.75 INPPL1 (0.55) HPGDCYP1A2CYP3A4CYP2C19INPPL1
Biphenyl SCHEMBL27668250 0.74 KDM4E (0.53) HPGDINPPL1INPP5AKDM4EMAPT
Biphenyl SCHEMBL9637830 0.74 SRC (0.64) CYP1A2CYP3A4CYP2C9CYP2C19INPPL1
SCHEMBL7591862 0.74 INPPL1 (0.48) ACHEHPGDCYP2C9CYP2C19INPPL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001789-B Halogen-free flame-retardant composition 路博润先进材料公司 2021-02-02 CN disclosed
US-5550179-A Water based lacquer compositions and method of making and using same SROURIAN NICHAN (US) 1996-08-27 US disclosed