Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRACR2A | Q9BSW2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639005 | 0.75 | DHODH (0.44) | DHODHHTTCRACR2ANPC1RAB9A | |
| SCHEMBL1027062 | 0.71 | DHODH (0.44) | DHODHKMT2ALMNASMN1; SMN2TAS1R3 | |
| SCHEMBL9638659 | 0.71 | LMNA (0.56) | DHODHNPC1RAB9ALMNATAS1R3 | |
| SCHEMBL8063449 | 0.71 | DHODH (0.73) | DHODHHTTMEN1KMT2ACRACR2A | |
| SCHEMBL8045714 | 0.71 | RAB9A (0.47) | DHODHHTTMEN1KMT2ACRACR2A | |
| SCHEMBL8045733 | 0.71 | CRACR2A (0.51) | DHODHHTTCRACR2ANPC1RAB9A | |
| SCHEMBL14648620 | 0.70 | DHODH (0.43) | DHODHHTTCRACR2ANPC1RAB9A | |
| SCHEMBL8057748 | 0.70 | RAB9A (0.53) | DHODHHTTMEN1KMT2ACRACR2A | |
| SCHEMBL9639001 | 0.70 | LMNA (0.62) | DHODHHTTNPC1RAB9ALMNA | |
| SCHEMBL27513121 | 0.70 | DHODH (0.46) | DHODHCRACR2ALMNATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506249-A | ANTIINFLAMMATORY, ANTIPROLIFERATIVE AND ANTITUMOR ACTIVITY | ROUSSEL UCLAF (FR) | 1996-04-09 | — | — | US | claimed |