Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942702 | 0.88 | EPHX2 (0.38) | ALOX5EPHX2ALDH1A1MAPT | |
| SCHEMBL8942383 | 0.88 | ALDH1A1 (0.45) | ALOX5LTA4HEPHX2ALDH1A1MAPT | |
| SCHEMBL8942307 | 0.88 | KLKB1 (0.43) | ALOX5LTA4HEPHX2ALDH1A1MAPT | |
| SCHEMBL8783508 | 0.85 | ALOX5 (0.54) | ALOX5ALDH1A1MAPT | |
| SCHEMBL8942749 | 0.83 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL8942397 | 0.80 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL8942621 | 0.80 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL8942835 | 0.80 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL8942609 | 0.80 | ALOX5 (0.52) | ALOX5ALDH1A1MAPT | |
| SCHEMBL8782994 | 0.74 | KLKB1 (0.48) | ALOX5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |