Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942702 | 0.88 | EPHX2 (0.38) | KLKB1ALDH1A1MAPTMAPK1ALOX5 | |
| SCHEMBL8942311 | 0.88 | ALOX5 (0.49) | ALDH1A1MAPTALOX5EPHX2LTA4H | |
| SCHEMBL8942383 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MAPTNPSR1MAPK1ALOX5 | |
| SCHEMBL8782994 | 0.85 | KLKB1 (0.48) | KLKB1ALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL8942484 | 0.80 | PARP10 (0.50) | ALDH1A1ALOX5NPC1HPGDRAB9A | |
| SCHEMBL8942399 | 0.78 | CTNNB1 (0.52) | ALDH1A1MAPTNPSR1MAPK1HPGD | |
| SCHEMBL8783508 | 0.75 | ALOX5 (0.54) | ALDH1A1MAPTALOX5 | |
| SCHEMBL8783029 | 0.75 | ALDH1A1 (0.50) | KLKB1ALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL8782600 | 0.75 | KLKB1 (0.44) | KLKB1ALDH1A1MAPTALOX5HPGD | |
| SCHEMBL4155326 | 0.74 | PARP10 (0.50) | KLKB1ALDH1A1MAPTNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |