Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782305 | 0.82 | KDM4E (0.55) | CTNNB1MAPTLMNAMEN1KMT2A | |
| SCHEMBL8942484 | 0.82 | PARP10 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8942625 | 0.80 | ALOX5 (0.47) | CTNNB1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8942302 | 0.80 | ALOX5 (0.41) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8942307 | 0.78 | KLKB1 (0.43) | MAPTMAPK1ALDH1A1HPGDTSHR | |
| SCHEMBL8942657 | 0.74 | ALOX5 (0.56) | SMN1; SMN2ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL8782496 | 0.74 | KDM4E (0.46) | CTNNB1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL9365722 | 0.73 | CTNNB1 (0.51) | CTNNB1MAPTLMNAMEN1KMT2A | |
| SCHEMBL8783366 | 0.73 | KDM4E (0.46) | CTNNB1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8782612 | 0.72 | HSD17B10 (0.52) | MEN1KMT2AMAPK1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |