Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 6/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10888613 | 0.92 | FAAH (0.53) | CNR1LMNAPKMALDH1A1FAAH | |
| SCHEMBL19194057 | 0.92 | FAAH (0.53) | CNR1LMNAPKMALDH1A1FAAH | |
| SCHEMBL13328249 | 0.88 | LMNA (0.60) | CNR1LMNAPKMALDH1A1FAAH | |
| SCHEMBL1518045 | 0.88 | ALDH1A1 (0.57) | CNR1LMNAPKMALDH1A1FAAH | |
| SCHEMBL20206555 | 0.86 | CNR1 (0.56) | CNR1LMNAPKMALDH1A1FAAH | |
| SCHEMBL23472179 | 0.85 | FAAH (0.61) | CNR1FAAHCASP2DNM1NAAA | |
| SCHEMBL27998259 | 0.85 | FAAH (0.56) | CNR1LMNAPKMFAAHCASP2 | |
| SCHEMBL19249120 | 0.85 | CASP2 (0.58) | CNR1LMNAPKMALDH1A1FAAH | |
| SCHEMBL24826063 | 0.84 | CNR1 (0.52) | CNR1LMNAPKMALDH1A1FAAH | |
| SCHEMBL4904632 | 0.84 | CASP2 (0.62) | CNR1LMNAPKMALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968212-B2 | Compounds having estrogen receptor alpha degradation activity and uses thereof | ACCUTAR BIOTECHNOLOGY INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-9981954-B2 | 2-(pyrazin-2-ylcarbonylaminomethyl) benzimidazolium compounds as epithelial sodium channel inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-05-29 | — | — | US | disclosed |
| US-20180002314-A1 | 2-(PYRAZIN-2-YLCARBONYLAMINOMETHYL) BENZIMIDAZOLIUM COMPOUNDS AS EPITHELIAL SODIUM CHANNEL INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-01-04 | — | — | US | disclosed |
| WO-2017176040-A1 | HETEROCYCLIC COMPOUND DECOMPOSING RAS AND USES THEREOF | 연세대학교 산학협력단 | 2017-10-12 | — | — | WO | disclosed |
| US-9290584-B2 | Polyalkylene carboxylic acid polyamine additives for fouling mitigation in hydrocarbon refining processes | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-03-22 | — | — | US | disclosed |
| US-20130008830-A1 | POLYALKYLENE CARBOXYLIC ACID POLYAMINE ADDITIVES FOR FOULING MITIGATION IN HYDROCARBON REFINING PROCESSES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-01-10 | — | — | US | disclosed |
| EP-0699187-A1 | DERIVATIVES OF -g(b), -g(b)-DIMETHYL-4-PIPERIDINEETHANAMINE AS INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS | FOURNIER IND & SANTE (FR) | 1996-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130008830-A1 | POLYALKYLENE CARBOXYLIC ACID POLYAMINE ADDITIVES FOR FOULING MITIGATION IN HYDROCARBON REFINING PROCESSES | PFAS, PCBP1, PARG | CNR1 3052/4885LMNA 1050/4885PKM 355/4885 |
| US-20180002314-A1 | 2-(PYRAZIN-2-YLCARBONYLAMINOMETHYL) BENZIMIDAZOLIUM COMPOUNDS AS EPITHELIAL SODIUM CHANNEL INHIBITORS | SCNN1A, TRPV1, SCNN1B | CNR1 3767/4885LMNA 560/4885PKM 356/4885 |
| US-10968212-B2 | Compounds having estrogen receptor alpha degradation activity and uses thereof | ESR2, ESRRG, ESR1 | CNR1 487/4885LMNA 1648/4885PKM 2868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.