Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RHOA | P61586 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | EPOR | P19235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783371 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL6829496 | 0.90 | LMNA (0.64) | ALDH1A1KDM4ESMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL6829500 | 0.90 | LMNA (0.64) | ALDH1A1KDM4ESMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL1206897 | 0.89 | ALOX5 (0.68) | ALDH1A1KDM4ESMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL30014477 | 0.89 | ALOX5 (0.68) | ALDH1A1KDM4ESMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL1206895 | 0.89 | ALOX5 (0.68) | ALDH1A1KDM4ESMN1; SMN2ALOX5PTGS1 | |
| Hydrochloric Acid SCHEMBL11175049 | 0.88 | ALOX5 (0.67) | ALDH1A1KDM4ESMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL9514221 | 0.87 | ALOX5 (0.56) | ALDH1A1KDM4ESMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL9514207 | 0.87 | ALOX5 (0.56) | ALDH1A1KDM4ESMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL6827969 | 0.87 | KMO (0.58) | ALDH1A1KDM4ESMN1; SMN2ALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |