SCHEMBL8943476

SCHEMBL8943476

C=CCC(=O)OC(Oc1ccccc1)c1ccccc1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 3/20 0.35
HTT P42858 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
THRB P10828 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 1/20 0.33
AKR1B1 P15121 1/20 0.33
CASP1 P29466 1/20 0.32
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32
CYP2C19 P33261 1/20 0.32
TSHR P16473 1/20 0.32
GLA P06280 1/20 0.32
RAB9A P51151 1/20 0.32
PPARA Q07869 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL982078 0.75 GABRA1 (0.46) ALDH1A1HPGDSMN1; SMN2KDM4EALOX15
SCHEMBL8943022 0.71 TSHR (0.37) HPGDSMN1; SMN2THRBKDM4EMEN1
SCHEMBL163578 0.69 ALDH1A1 (0.50) GAAALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL23529518 0.68 CRHBP (0.49) GAAALDH1A1HPGDHTTSMN1; SMN2
Bicarbonate SCHEMBL27510048 0.68 ALDH1A1 (0.49) GAAALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL2788102 0.68 ALDH1A1 (0.49) GAAALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL7249737 0.68 PPARG (0.50) GAAALDH1A1HTTSMN1; SMN2THRB
SCHEMBL1076486 0.66 GAA (0.48) GAAALDH1A1HTTSMN1; SMN2THRB
SCHEMBL16672943 0.66 HCAR2 (0.53) GAAALDH1A1KDM4EKMT2AHSD17B10
SCHEMBL16672538 0.66 KDM4E (0.39) GAAALDH1A1SMN1; SMN2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467721-B1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO (JP) 1996-03-27 EP disclosed
US-5480580-A COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY MITSUBISHI RAYON COMPANY LTD. (JP) 1996-01-02 US disclosed
EP-0467721-A1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD (JP) 1992-01-22 EP disclosed