Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943826 | 0.85 | ALDH1A1 (0.40) | ALDH1A1ITGB1ITGA4CYP3A4F2 | |
| SCHEMBL7439248 | 0.83 | MEN1 (0.46) | ALDH1A1RAB9ASMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL9525464 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30797543 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20400038 | 0.83 | BCL2A1 (0.44) | ALDH1A1HTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8707172 | 0.83 | MT-CO2 (0.35) | ALDH1A1MAPTITGB1ITGA4LMNA | |
| SCHEMBL7758742 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30358877 | 0.82 | BCL2A1 (0.43) | ALDH1A1HTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31464829 | 0.82 | BCL2A1 (0.43) | ALDH1A1HTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9525310 | 0.81 | RXRA (0.42) | ALDH1A1HTTRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532353-A | Process for the preparation of halogenated β-lactam compounds | BIOCHIMICA OPOS SPA (IT) | 1996-07-02 | — | — | US | disclosed |
| EP-0570058-A2 | Process for the preparation of halogenated beta-lactam compounds | BIOCHIMICA OPOS SPA (IT) | 1993-11-18 | — | — | EP | disclosed |