Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797543 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HTTRAB9ASMN1; SMN2BCL2A1 | |
| SCHEMBL7758742 | 0.88 | ALDH1A1 (0.42) | ALDH1A1HTTRAB9ASMN1; SMN2BCL2A1 | |
| SCHEMBL9525310 | 0.87 | RXRA (0.42) | ALDH1A1HTTRAB9ASMN1; SMN2BCL2A1 | |
| SCHEMBL20400038 | 0.84 | BCL2A1 (0.44) | ALDH1A1HTTRAB9ASMN1; SMN2BCL2A1 | |
| SCHEMBL10401421 | 0.84 | MTNR1A (0.40) | ALDH1A1F2MAPTLMNARIPK1 | |
| SCHEMBL3657533 | 0.83 | MT-CO2 (0.46) | BCL2A1F2ROCK2LIMK1ROCK1 | |
| SCHEMBL1624311 | 0.83 | SMN1; SMN2 (0.51) | ALDH1A1HTTSMN1; SMN2F2TSHR | |
| SCHEMBL8943566 | 0.83 | ALDH1A1 (0.42) | ALDH1A1HTTRAB9ASMN1; SMN2BCL2A1 | |
| SCHEMBL31464829 | 0.83 | BCL2A1 (0.43) | ALDH1A1HTTRAB9ASMN1; SMN2BCL2A1 | |
| SCHEMBL30358877 | 0.83 | BCL2A1 (0.43) | ALDH1A1HTTRAB9ASMN1; SMN2BCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373814-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | Novartis AG (CH) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023002409-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |