SCHEMBL8943640

SCHEMBL8943640

CN(CCC(=O)O)c1ccc(N)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP14 P50281 1/20 0.43
ALDH1A1 P00352 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
MAPK1 P28482 3/20 0.43
CYP3A4 P08684 3/20 0.43
TP53 P04637 1/20 0.43
ALOX15 P16050 1/20 0.43
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
HIF1A Q16665 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
PHLPP2 Q6ZVD8 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
TSHR P16473 2/20 0.39
PSMD14 O00487 1/20 0.39
RECQL P46063 1/20 0.39
GFER P55789 1/20 0.39
PPIB P23284 1/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13688687 0.83 KMT2A (0.48) MMP14ALDH1A1KDM4EL3MBTL1TSHR
SCHEMBL2637695 0.82 TP53 (0.47) MMP14ALDH1A1CYP3A4TP53L3MBTL1
SCHEMBL10906746 0.81 RAB9A (0.52) MMP14ALDH1A1MAPTL3MBTL1
SCHEMBL10906239 0.81 HPGD (0.53) MMP14ALDH1A1MAPTL3MBTL1LMNA
SCHEMBL5726224 0.81 TDP1 (0.46) ALDH1A1TDP1MAPK1CYP3A4TP53
Hydrochloric Acid SCHEMBL6831468 0.81 TP53 (0.46) MMP14ALDH1A1CYP3A4TP53L3MBTL1
SCHEMBL10951350 0.80 HPGD (0.52) MMP14ALDH1A1MAPTL3MBTL1LMNA
SCHEMBL16914897 0.80 ALDH1A1 (0.59) ALDH1A1TDP1MAPK1CYP3A4TP53
SCHEMBL5899291 0.79 MMP14 (0.51) MMP14ALDH1A1TDP1MAPK1CYP3A4
SCHEMBL8916917 0.79 LMNA (0.50) TP53MAPTLMNAFFAR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5512410-A Heat image separation with phenolic thermal solvents and dye releasing couplers EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed
US-5512414-A ELEMENT CONTAINING MORDANT LAYER FOR BINDING DIFFUSIBLE DYES, LAYER CONTAINING SOLID PARTICLE DISPERSION OF DIFFUSIBLE DYE FORMING COMPOUND, BARRIER LAYER WHICH BLOCKS DIFFUSION OF DYE OUT OF ELEMENT EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed
US-5494775-A DIFFUSION TRANSFER PROCESS FOR COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1996-02-27 US disclosed
US-5455140-A Image quality, preferred hues EASTMAN KODAK COMPANY (US) 1995-10-03 US disclosed
US-5441854-A Photographic image forming process utilizing a barrier layer for diffusible dye containment EASTMAN KODAK COMPANY (US) 1995-08-15 US disclosed
US-5370967-A Polymeric barrier to control diffusion EASTMAN KODAK COMPANY (US) 1994-12-06 US disclosed
US-5360695-A Noncrystallizing EASTMAN KODAK COMPANY (US) 1994-11-01 US disclosed
US-5356750-A Dye releasing couplers for heat image separation systems EASTMAN KODAK COMPANY (US) 1994-10-18 US disclosed
EP-0608825-A1 Solid particle thermal solvent dispersions EASTMAN KODAK COMPANY (US) 1994-08-03 EP disclosed
US-5322758-A Integral color diffusion transfer element for large volume development EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
EP-0590567-A1 Integral color diffusion transfer element for large volume development EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
EP-0590566-A1 Barrier layer for dye containment in photographic elements EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
EP-0590565-A1 Image separation system for large volume development EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
US-5288745-A Diffusion transfer for color photography; polymeric mordant dye barrier layers EASTMAN KODAK COMPANY (US) 1994-02-22 US disclosed
US-4110355-A COLOR COUPLERS POLAROID CORPORATION (US) 1978-08-29 US disclosed