Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27473794 | 0.98 | MMP14 (0.50) | MMP14ALDH1A1HSD17B10TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11503465 | 0.89 | MMP14 (0.61) | MMP14ALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL61402 | 0.80 | ALDH1A1 (0.55) | MMP14ALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL13688687 | 0.80 | KMT2A (0.48) | MMP14ALDH1A1TSHRKMT2AL3MBTL1 | |
| SCHEMBL2637695 | 0.80 | TP53 (0.47) | MMP14ALDH1A1TSHRTP53KMT2A | |
| SCHEMBL8943640 | 0.79 | MMP14 (0.43) | MMP14ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL10906746 | 0.79 | RAB9A (0.52) | MMP14ALDH1A1KMT2ANPC1L3MBTL1 | |
| SCHEMBL10906239 | 0.79 | HPGD (0.53) | MMP14ALDH1A1KMT2ANPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6831468 | 0.78 | TP53 (0.46) | MMP14ALDH1A1TSHRTP53KMT2A | |
| SCHEMBL10951350 | 0.77 | HPGD (0.52) | MMP14ALDH1A1KMT2ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060240455-A1 | OXAZINE DERIVATIVES | EVOTEC AG (DE) | 2006-10-26 | — | — | US | disclosed |
| US-7101999-B2 | Oxazine derivatives | EVOTEC AG (DE) | 2006-09-05 | — | — | US | disclosed |
| EP-1535967-A1 | Oxazine derivatives | Evotec OAI AG (DE) | 2005-06-01 | — | — | EP | disclosed |
| EP-1317511-B1 | OXAZINE DERIVATIVES | EVOTEC AG (DE) | 2005-01-19 | — | — | EP | disclosed |
| US-20040029837-A1 | Oxazine derivatives | EVOTEC AG (DE) | 2004-02-12 | — | — | US | disclosed |
| WO-2003080736-A1 | USE OF OXAZINE DYES AS MARKING GROUPS FOR SINGLE MOLECULE ANALYSIS | GNOTHIS HOLDING SA (CH) | 2003-10-02 | — | — | WO | disclosed |
| EP-1317511-A1 | OXAZINE DERIVATIVES | Evotec BioSystems AG (DE) | 2003-06-11 | — | — | EP | disclosed |
| EP-1213328-A1 | Oxazine derivatives | Evotec OAI AG (DE) | 2002-06-12 | — | — | EP | disclosed |
| WO-2002020670-A1 | OXAZINE DERIVATIVES | EVOTEC OAI AG (DE) | 2002-03-14 | — | — | WO | disclosed |
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0319733-A2 | Process, modified rubbers and rubber compositions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029837-A1 | Oxazine derivatives | OXA1L, HELZ, IKZF2 | MMP14 950/4885ALDH1A1 156/4885HSD17B10 964/4885 |
| US-20060240455-A1 | OXAZINE DERIVATIVES | OXA1L, HELZ, SPOP | MMP14 638/4885ALDH1A1 116/4885HSD17B10 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.