SCHEMBL8943774

SCHEMBL8943774

COc1ccc(N(c2ccccc2)c2ccc(OCCCOc3ccc(N(c4ccccc4)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.57
MAPT P10636 2/20 0.57
HPGD P15428 1/20 0.57
ATM Q13315 1/20 0.57
DRD2 P14416 1/20 0.56
DRD4 P21917 1/20 0.56
DRD3 P35462 1/20 0.56
TSHR P16473 1/20 0.51
LTA4H P09960 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
KCNH2 Q12809 2/20 0.49
RECQL P46063 1/20 0.49
KCNA3 P22001 1/20 0.47
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943912 0.96 DRD2 (0.56) L3MBTL1MAPTHPGDATMDRD2
SCHEMBL8943641 0.95 LTA4H (0.58) L3MBTL1MAPTHPGDATMDRD2
SCHEMBL8943988 0.95 L3MBTL1 (0.59) L3MBTL1MAPTHPGDATMDRD2
SCHEMBL8943762 0.93 MAPT (0.54) L3MBTL1MAPTHPGDATMDRD2
SCHEMBL8944175 0.91 L3MBTL1 (0.59) L3MBTL1MAPTHPGDATMDRD2
SCHEMBL8943810 0.91 KCNA3 (0.56) L3MBTL1MAPTHPGDATMDRD2
SCHEMBL8943684 0.90 LTA4H (0.58) L3MBTL1MAPTHPGDATMDRD2
SCHEMBL8943653 0.87 LTA4H (0.55) L3MBTL1MAPTDRD2DRD4DRD3
SCHEMBL12012640 0.87 LTA4H (0.55) L3MBTL1MAPTDRD2DRD4DRD3
SCHEMBL8943807 0.87 AHR (0.53) L3MBTL1MAPTHPGDATMDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed