SCHEMBL8943652

SCHEMBL8943652

c1ccc2c(Nc3ccc(OCCCCCCOc4ccc(Nc5c6ccccc6cc6ccccc56)cc4Nc4c5ccccc5cc5ccccc45)c(Nc4c5ccccc5cc5ccccc45)c3)c3ccccc3cc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 2/20 0.38
SLC6A4 P31645 2/20 0.38
CNR2 P34972 3/20 0.37
KCNA3 P22001 1/20 0.37
HRH3 Q9Y5N1 6/20 0.36
HTR2A P28223 2/20 0.36
HTR7 P34969 2/20 0.36
HTR6 P50406 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
HRH1 P35367 1/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
RAD52 P43351 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943787 0.81 FADS1 (0.49) HTR1BSLC6A4CNR2KCNA3HRH3
SCHEMBL8943911 0.80 RAB9A (0.40) HTR1BSLC6A4CNR2KCNA3KMT2A
SCHEMBL8944034 0.78 ALDH1A1 (0.50) CNR2KCNA3HRH3KMT2AMEN1
SCHEMBL8944255 0.74 ALDH1A1 (0.47) KMT2AMEN1KDM4EPOLBMAPT
SCHEMBL8943966 0.73 CDC25B (0.55) KMT2AMEN1L3MBTL1SLC2A1ABCG2
SCHEMBL8148202 0.73 KDM1A (0.54) KMT2AMEN1KDM4EPOLBMAPT
SCHEMBL8944041 0.69 ALDH1A1 (0.42) SLC6A4KCNA3HRH3HTR2AHTR7
SCHEMBL8148203 0.69 KDM1A (0.46) HTR2AKMT2AMEN1KDM4EPOLB
SCHEMBL8943794 0.69 L3MBTL4 (0.41) KMT2AMEN1KDM4EMAPTL3MBTL1
SCHEMBL8943812 0.69 L3MBTL4 (0.41) KMT2AMEN1KDM4EMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed