SCHEMBL8943706

SCHEMBL8943706

COc1ccc(N(c2ccc(C)cc2)c2ccc(OCCOc3ccc(N(c4ccc(C)cc4)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.56
NPC1 O15118 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
LMNA P02545 2/20 0.47
GAA P10253 1/20 0.47
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
DRD3 P35462 1/20 0.46
RELA Q04206 1/20 0.46
KMT2A Q03164 2/20 0.44
HPGD P15428 4/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
KCNH2 Q12809 1/20 0.44
MCHR1 Q99705 1/20 0.43
ATM Q13315 1/20 0.42
APP P05067 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944275 0.95 ACHE (0.54) ACHENPC1L3MBTL1LMNAGAA
SCHEMBL8943677 0.95 ACHE (0.54) ACHENPC1L3MBTL1LMNAGAA
SCHEMBL8944204 0.89 ACHE (0.56) ACHELMNAGAARELAHPGD
SCHEMBL20251336 0.89 DRD2 (0.46) ACHENPC1L3MBTL1DRD2DRD4
SCHEMBL10065624 0.88 ACHE (0.71) ACHENPC1LMNAGAARELA
SCHEMBL348291 0.88 ACHE (0.71) ACHENPC1LMNAGAARELA
SCHEMBL5929473 0.88 ACHE (0.71) ACHENPC1L3MBTL1LMNAGAA
SCHEMBL172190 0.88 ACHE (0.71) ACHENPC1LMNAGAARELA
SCHEMBL19958553 0.88 ACHE (0.71) ACHENPC1LMNAGAARELA
SCHEMBL12545287 0.88 ACHE (0.71) ACHENPC1LMNAGAARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed