SCHEMBL8944204

SCHEMBL8944204

CCOc1ccc(N(c2ccc(C)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.56
NQO1 P15559 1/20 0.52
LMNA P02545 2/20 0.50
MAPT P10636 4/20 0.47
GAA P10253 2/20 0.47
RELA Q04206 1/20 0.46
TP53 P04637 1/20 0.45
THRB P10828 1/20 0.45
ESR1 P03372 2/20 0.45
ALDH1A1 P00352 2/20 0.45
AHR P35869 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943626 0.92 NQO1 (0.61) NQO1LMNAMAPTGAAESR1
SCHEMBL8944288 0.92 NQO1 (0.61) NQO1LMNAMAPTGAAESR1
SCHEMBL8943706 0.89 ACHE (0.56) ACHELMNAMAPTGAARELA
SCHEMBL12545287 0.88 ACHE (0.71) ACHELMNAMAPTGAARELA
SCHEMBL348291 0.88 ACHE (0.71) ACHELMNAMAPTGAARELA
SCHEMBL10065624 0.88 ACHE (0.71) ACHELMNAMAPTGAARELA
SCHEMBL172190 0.88 ACHE (0.71) ACHELMNAMAPTGAARELA
SCHEMBL19958553 0.88 ACHE (0.71) ACHELMNAMAPTGAARELA
SCHEMBL8943677 0.87 ACHE (0.54) ACHELMNAMAPTGAARELA
SCHEMBL8944275 0.87 ACHE (0.54) ACHELMNAMAPTGAARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed