SCHEMBL8943823

SCHEMBL8943823

COc1ccc(N(c2ccc(C)cc2)c2ccc(OCC(C)Oc3ccc(N(c4ccc(C)cc4)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.44
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
GAA P10253 1/20 0.40
CYP2C9 P11712 2/20 0.40
TSHR P16473 1/20 0.40
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
HPGD P15428 3/20 0.38
MAPT P10636 3/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
RELA Q04206 1/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
CYP2C19 P33261 1/20 0.38
TP53 P04637 1/20 0.37
THRB P10828 1/20 0.37
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944273 0.88 KMT2A (0.42) LMNACYP2C9TSHRMTNR1AMTNR1B
SCHEMBL8641671 0.84 USP2 (0.46) ACHELMNACYP2C9TSHRMAPT
SCHEMBL418159 0.84 CYP2C9 (0.52) ALDH1A1GAACYP2C9TSHRMTNR1A
SCHEMBL13053151 0.82 TP53 (0.37) ALDH1A1LMNACYP2C9TSHRHPGD
SCHEMBL8944304 0.81 LMNA (0.44) LMNACYP2C9HPGDMAPTKDM4E
SCHEMBL9344357 0.81 NQO1 (0.50) ALDH1A1GAACYP2C9TSHRMTNR1A
SCHEMBL9348566 0.81 NQO1 (0.50) ALDH1A1GAACYP2C9TSHRMTNR1A
SCHEMBL9343776 0.81 NQO1 (0.50) ALDH1A1GAACYP2C9TSHRMTNR1A
SCHEMBL8943750 0.79 MAPT (0.55) ALDH1A1LMNACYP2C9TSHRHPGD
SCHEMBL8944204 0.79 ACHE (0.56) ACHEALDH1A1LMNAGAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed