SCHEMBL8944273

SCHEMBL8944273

COc1ccc(N(c2ccccc2)c2ccc(OCC(C)Oc3ccc(N(c4ccccc4)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.40
TSHR P16473 2/20 0.40
CYP2C9 P11712 1/20 0.40
MTNR1A P48039 2/20 0.39
MTNR1B P49286 2/20 0.39
PBRM1 Q86U86 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
XBP1 P17861 1/20 0.38
DRD2 P14416 1/20 0.38
DRD4 P21917 1/20 0.38
DRD3 P35462 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944304 0.94 LMNA (0.44) L3MBTL1LMNACYP2C9POLBMAPT
SCHEMBL8943823 0.88 ACHE (0.44) KMT2ALMNATSHRCYP2C9MTNR1A
SCHEMBL8436935 0.88 LMNA (0.52) KMT2ALMNATSHRCYP2C9MTNR1A
SCHEMBL8436949 0.88 LMNA (0.52) KMT2ALMNATSHRCYP2C9MTNR1A
SCHEMBL418159 0.84 CYP2C9 (0.52) KMT2ATSHRCYP2C9MTNR1AMTNR1B
SCHEMBL9348566 0.81 NQO1 (0.50) TSHRCYP2C9MTNR1AMTNR1BPOLB
SCHEMBL9344357 0.81 NQO1 (0.50) TSHRCYP2C9MTNR1AMTNR1BPOLB
SCHEMBL9343776 0.81 NQO1 (0.50) TSHRCYP2C9MTNR1AMTNR1BPOLB
SCHEMBL8943750 0.79 MAPT (0.55) KMT2ALMNATSHRCYP2C9POLB
SCHEMBL8943988 0.79 L3MBTL1 (0.59) KMT2AL3MBTL1LMNATSHRCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed