SCHEMBL8943830

SCHEMBL8943830

Cc1ccc(Nc2ccc(Oc3cccc(Oc4ccc(Nc5ccc(C)cc5)cc4Nc4ccc(C)cc4)c3)c(Nc3ccc(C)cc3)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.43
GAA P10253 3/20 0.40
IDO1 P14902 2/20 0.40
MAPT P10636 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
EGFR P00533 3/20 0.39
ERBB2 P04626 2/20 0.39
ERBB3 P21860 2/20 0.39
ERBB4 Q15303 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SNCA P37840 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
G6PD P11413 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943647 0.89 AKR1C3 (0.43) HPGDGAAMAPTTDP1NPSR1
SCHEMBL8943958 0.86 RAB9A (0.52) GAAMAPTTDP1NPSR1EGFR
SCHEMBL8943842 0.85 SIRT2 (0.39) HPGDGAAIDO1MAPTNPSR1
SCHEMBL8944048 0.84 AKR1C3 (0.40) HPGDGAAMAPTTDP1EGFR
SCHEMBL8943837 0.80 GAA (0.42) HPGDGAAMAPTTDP1EGFR
SCHEMBL8944014 0.76 HPGD (0.42) HPGDGAAMAPTTDP1NPSR1
SCHEMBL8943616 0.76 MAPT (0.59) GAAMAPTTDP1NPSR1EGFR
SCHEMBL8943784 0.75 EGFR (0.44) HPGDMAPTTDP1EGFRERBB2
SCHEMBL8943646 0.74 L3MBTL4 (0.42) HPGDGAAMAPTTDP1EGFR
SCHEMBL8943600 0.74 HPGD (0.41) HPGDGAAMAPTTDP1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed