SCHEMBL8943842

SCHEMBL8943842

Cc1ccc(Nc2ccc(Oc3cccc(Oc4ccc(N(c5ccccc5)c5ccccc5)cc4)c3)c(Nc3ccc(C)cc3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
FFAR1 O14842 1/20 0.38
HPGD P15428 1/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HTT P42858 1/20 0.37
CYP1A2 P05177 1/20 0.37
MAPT P10636 2/20 0.36
TP53 P04637 1/20 0.36
HSD17B1 P14061 2/20 0.36
HSD17B2 P37059 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944031 0.86 MAPT (0.45) ALDH1A1KDM4EPOLBGAANPSR1
SCHEMBL8943830 0.85 HPGD (0.43) SIRT2SIRT1HPGDALDH1A1KDM4E
SCHEMBL8943701 0.83 FGFR2 (0.44) ALDH1A1KDM4EGAANPSR1HTT
SCHEMBL8943647 0.81 AKR1C3 (0.43) HPGDKDM4EPOLBGAANPSR1
SCHEMBL8943630 0.81 DRD2 (0.39) SIRT2HPGDHTTMAPTTP53
SCHEMBL8944048 0.77 AKR1C3 (0.40) HPGDPOLBGAAMAPTL3MBTL1
SCHEMBL8943958 0.76 RAB9A (0.52) ALDH1A1KDM4EPOLBGAANPSR1
SCHEMBL20059338 0.75 HTT (0.55) FFAR1ALDH1A1KDM4EPOLBCYP2C9
SCHEMBL23254850 0.74 HTT (0.52) FFAR1ALDH1A1KDM4EPOLBCYP2C9
SCHEMBL14732511 0.74 HTT (0.52) FFAR1ALDH1A1KDM4EPOLBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed