SCHEMBL8943630

SCHEMBL8943630

Cc1ccc(Nc2ccc(OCCOc3ccc(N(c4ccccc4)c4ccccc4)cc3)c(Nc3ccc(C)cc3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 3/20 0.39
DRD4 P21917 3/20 0.39
DRD3 P35462 3/20 0.39
HPGD P15428 1/20 0.39
HRH3 Q9Y5N1 2/20 0.39
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
TP53 P04637 1/20 0.38
KMT2A Q03164 1/20 0.38
SIRT2 Q8IXJ6 1/20 0.37
MAPT P10636 2/20 0.37
ADAMTS5 Q9UNA0 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
ACP1 P24666 1/20 0.35
HRH2 P25021 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
EGFR P00533 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944076 0.87 MAPT (0.43) DRD2DRD4DRD3HPGDRAB9A
SCHEMBL8943663 0.83 RAB9A (0.41) DRD2DRD4DRD3RAB9ANPC1
SCHEMBL8944014 0.82 HPGD (0.42) HPGDRAB9ANPC1KMT2ASIRT2
SCHEMBL8943842 0.81 SIRT2 (0.39) HPGDRAB9ANPC1TP53SIRT2
SCHEMBL8944086 0.80 MAPT (0.49) HPGDRAB9ANPC1TP53KMT2A
SCHEMBL8943885 0.79 RAB9A (0.39) RAB9ANPC1KMT2AMAPTMAPK1
SCHEMBL8944352 0.79 EGFR (0.48) RAB9ANPC1KMT2ASIRT2MAPT
SCHEMBL8943646 0.78 L3MBTL4 (0.42) HPGDRAB9ANPC1KMT2ASIRT2
SCHEMBL8943600 0.78 HPGD (0.41) HPGDRAB9ANPC1KMT2AMAPT
SCHEMBL8943794 0.77 L3MBTL4 (0.41) HPGDRAB9ANPC1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed