SCHEMBL8944048

SCHEMBL8944048

Cc1ccc(Nc2ccc(Oc3ccc(-c4ccc(Oc5ccc(Nc6ccc(C)cc6)cc5Nc5ccc(C)cc5)cc4)cc3)c(Nc3ccc(C)cc3)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
ACP1 P24666 1/20 0.40
FGFR2 P21802 1/20 0.40
HPGD P15428 1/20 0.39
KCNH2 Q12809 4/20 0.38
HTR2A P28223 2/20 0.38
SLC6A4 P31645 2/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
TTBK1 Q5TCY1 1/20 0.38
TTBK2 Q6IQ55 1/20 0.38
PKM P14618 1/20 0.38
POLB P06746 1/20 0.38
SNCA P37840 1/20 0.38
SCN5A Q14524 2/20 0.38
SCN9A Q15858 2/20 0.38
GAA P10253 2/20 0.38
G6PD P11413 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943647 0.95 AKR1C3 (0.43) AKR1C3AKR1C2HPGDKCNH2HTR2A
SCHEMBL8943613 0.88 RAB9A (0.53) AKR1C3AKR1C2ACP1FGFR2MEN1
SCHEMBL8943830 0.84 HPGD (0.43) AKR1C3AKR1C2HPGDMEN1KMT2A
SCHEMBL8943616 0.82 MAPT (0.59) AKR1C3AKR1C2FGFR2MEN1KMT2A
SCHEMBL8943895 0.78 UNG (0.46) HPGDGAAL3MBTL1
SCHEMBL8943842 0.77 SIRT2 (0.39) AKR1C3HPGDTTBK1TTBK2POLB
SCHEMBL8943737 0.76 LTA4H (0.46) HPGDMEN1KMT2AGAAMAPT
SCHEMBL8944057 0.76 GAA (0.41) AKR1C3AKR1C2ACP1FGFR2HPGD
SCHEMBL8944014 0.76 HPGD (0.42) AKR1C3AKR1C2HPGDMEN1KMT2A
SCHEMBL8943701 0.76 FGFR2 (0.44) ACP1FGFR2MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed