SCHEMBL8944193

SCHEMBL8944193

CCCCCCCCCCCCCCCCCC(Cl)C(Cl)(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.39
LMNA P02545 1/20 0.38
DNM1 Q05193 2/20 0.37
TSHR P16473 2/20 0.36
THRB P10828 1/20 0.36
LAP3 P28838 1/20 0.36
OPRM1 P35372 1/20 0.36
SMPD1 P17405 3/20 0.35
ALDH1A1 P00352 1/20 0.35
GPR84 Q9NQS5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22634846 1.00 FDPS (0.39) FDPSLMNADNM1TSHRTHRB
SCHEMBL25416009 1.00 FDPS (0.39) FDPSLMNADNM1TSHRTHRB
SCHEMBL11223579 1.00 FDPS (0.39) FDPSLMNADNM1TSHRTHRB
SCHEMBL9278253 0.98 OPRM1 (0.37) FDPSLMNADNM1TSHRTHRB
SCHEMBL9528056 0.91 DNM1 (0.35) FDPSDNM1TSHRALDH1A1
SCHEMBL16969571 0.83 FDPS (0.40) FDPSLMNADNM1GPR84
SCHEMBL16970104 0.83 FDPS (0.40) FDPSLMNADNM1GPR84
SCHEMBL7096584 0.81 LMNA (0.41) FDPSLMNADNM1TSHRTHRB
SCHEMBL10395459 0.81 LMNA (0.41) FDPSLMNADNM1TSHRTHRB
SCHEMBL686672 0.81 LMNA (0.41) FDPSLMNADNM1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5540843-A PRECIPITATION WITH DELTAHEDRAL HETEROBORANE ANIONS; REMOVAL FROM SOLUTION BY SORPTION ON ACTIVE CHARCOAL PLESEK JAROMIR (CS) 1996-07-30 US disclosed