SCHEMBL8944288

SCHEMBL8944288

CCOc1ccc(N(c2ccc(OC)cc2)c2ccc(OCC)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.61
MAPT P10636 3/20 0.53
GAA P10253 1/20 0.53
ESR1 P03372 2/20 0.50
TSHR P16473 2/20 0.50
AHR P35869 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 6/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
KDM4E B2RXH2 4/20 0.49
NPC1 O15118 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAPK1 P28482 1/20 0.49
CYP1A2 P05177 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943626 1.00 NQO1 (0.61) NQO1MAPTGAAESR1TSHR
SCHEMBL12012640 0.92 LTA4H (0.55) NQO1MAPTGAAESR1TSHR
SCHEMBL8944204 0.92 ACHE (0.56) NQO1MAPTGAAESR1TSHR
SCHEMBL8943653 0.92 LTA4H (0.55) NQO1MAPTGAAESR1TSHR
SCHEMBL3239122 0.91 NQO1 (0.74) NQO1MAPTTSHRTDP1ALDH1A1
SCHEMBL8944236 0.91 NQO1 (0.50) NQO1MAPTGAAESR1TSHR
1-Methoxy-4-Ethoxybenzene SCHEMBL354674 0.89 NQO1 (0.78) NQO1MAPTGAAESR1TSHR
SCHEMBL8943971 0.88 LTA4H (0.70) NQO1SMN1; SMN2LTA4H
SCHEMBL6233100 0.86 CA1 (0.65) MAPTGAATDP1ALDH1A1CYP3A4
SCHEMBL1573622 0.86 CA1 (0.65) MAPTGAATDP1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed