SCHEMBL8944236

SCHEMBL8944236

CCCOc1ccc(N(c2ccc(OC)cc2)c2ccc(OCC)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.50
ALDH1A1 P00352 6/20 0.49
KDM4E B2RXH2 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
MAPT P10636 3/20 0.46
GAA P10253 1/20 0.46
TSHR P16473 3/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 1/20 0.46
LTA4H P09960 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
ESR1 P03372 2/20 0.44
AHR P35869 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
NPC1 O15118 2/20 0.43
MAPK1 P28482 1/20 0.43
CYP1A2 P05177 1/20 0.43
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944354 0.94 TSHR (0.49) ALDH1A1KDM4ESMN1; SMN2MAPTTSHR
SCHEMBL8944288 0.91 NQO1 (0.61) NQO1ALDH1A1KDM4ESMN1; SMN2MAPT
SCHEMBL8943626 0.91 NQO1 (0.61) NQO1ALDH1A1KDM4ESMN1; SMN2MAPT
SCHEMBL8943807 0.87 AHR (0.53) MAPTTSHRLTA4HCYP3A4AHR
SCHEMBL8944313 0.87 AHR (0.53) MAPTTSHRLTA4HCYP3A4AHR
SCHEMBL8944178 0.87 LTA4H (0.55) NQO1ALDH1A1KDM4ESMN1; SMN2MAPT
SCHEMBL8943762 0.85 MAPT (0.54) ALDH1A1KDM4ESMN1; SMN2MAPTTSHR
1-Methoxy-4-Propoxybenzene SCHEMBL1324557 0.84 LTA4H (0.57) SMN1; SMN2MAPTTSHRLMNAHTT
SCHEMBL8944174 0.84 NR5A1 (0.55) MAPTGAATSHRLMNALTA4H
SCHEMBL8944204 0.84 ACHE (0.56) NQO1ALDH1A1MAPTGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed