SCHEMBL8943784

SCHEMBL8943784

Cc1ccc(Nc2ccc(OCc3cccc(COc4ccc(Nc5ccc(C)cc5)cc4Nc4ccc(C)cc4)c3)c(Nc3ccc(C)cc3)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EGFR P00533 8/20 0.44
ERBB2 P04626 6/20 0.44
CTSV O60911 4/20 0.43
CTSL P07711 4/20 0.43
MRGPRX4 Q96LA9 3/20 0.42
HPGD P15428 1/20 0.40
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
SGMS2 Q8NHU3 1/20 0.39
SLC2A1 P11166 1/20 0.39
GAK O14976 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944340 0.92 CTSV (0.44) EGFRERBB2CTSVCTSLALDH1A1
SCHEMBL8944045 0.90 CTSV (0.43) CTSVCTSLHPGDALDH1A1LMNA
SCHEMBL8943590 0.86 CTSV (0.47) EGFRERBB2CTSVCTSLMRGPRX4
SCHEMBL8943788 0.82 SGMS2 (0.41) CTSVCTSLMRGPRX4ALDH1A1LMNA
SCHEMBL8944014 0.82 HPGD (0.42) EGFRHPGDALDH1A1LMNACYP2C9
SCHEMBL8943646 0.80 L3MBTL4 (0.42) EGFRHPGDALDH1A1LMNACYP1A2
SCHEMBL8943600 0.80 HPGD (0.41) EGFRHPGDALDH1A1LMNACYP1A2
SCHEMBL8943794 0.79 L3MBTL4 (0.41) EGFRHPGDALDH1A1LMNACYP1A2
SCHEMBL8943812 0.79 L3MBTL4 (0.41) EGFRHPGDALDH1A1LMNACYP1A2
SCHEMBL8943884 0.78 HPGD (0.39) EGFRHPGDALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed