SCHEMBL8944379

SCHEMBL8944379

Cc1ccc(N(c2ccc(C)cc2)c2cccc(Oc3cccc(N(c4ccc(C)cc4)c4ccc(C)cc4)c3)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HSD17B1 P14061 3/20 0.42
HSD17B2 P37059 3/20 0.42
ALDH1A1 P00352 5/20 0.42
ADRA2A P08913 2/20 0.39
ADRA1A P35348 2/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
ADRA1D P25100 1/20 0.39
ADRA1B P35368 1/20 0.39
CETP P11597 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
TSHR P16473 1/20 0.37
ACHE P22303 1/20 0.36
TEAD4 Q15561 1/20 0.36
NR3C1 P04150 1/20 0.36
GAA P10253 2/20 0.36
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19596242 0.89 FFAR4 (0.46) HTTTDP1L3MBTL1HSD17B1HSD17B2
SCHEMBL10446068 0.89 FFAR4 (0.46) HTTTDP1L3MBTL1HSD17B1HSD17B2
SCHEMBL13837154 0.89 FFAR4 (0.46) HTTTDP1L3MBTL1HSD17B1HSD17B2
SCHEMBL8943776 0.88 HSD17B1 (0.50) HTTTDP1L3MBTL1HSD17B1HSD17B2
SCHEMBL13030516 0.85 HSD17B1 (0.57) HTTTDP1L3MBTL1HSD17B1HSD17B2
SCHEMBL12018970 0.84 PGR (0.46) HTTHSD17B1HSD17B2ALDH1A1ADRA2A
SCHEMBL14340638 0.84 ACHE (0.50) ADRA2AADRA1AADRA2BADRA2CADRA1D
SCHEMBL11887992 0.84 MAOB (0.42) ALDH1A1ADRA2AADRA1AADRA2BADRA2C
SCHEMBL8943978 0.84 MAOB (0.48) TDP1L3MBTL1ALDH1A1CETPSMN1; SMN2
SCHEMBL1817033 0.83 ALDH1A1 (0.46) HTTTDP1L3MBTL1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed