Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944902 | 0.88 | CYP2A13 (0.39) | NISCH | |
| SCHEMBL8944755 | 0.87 | LMNA (0.40) | NISCH | |
| SCHEMBL8944813 | 0.84 | NISCH (0.47) | NISCH | |
| SCHEMBL8944702 | 0.83 | NISCH (0.42) | NISCH | |
| SCHEMBL2387265 | 0.81 | KDM4E (0.44) | NISCH | |
| SCHEMBL8944628 | 0.79 | ADRA2A (0.41) | NISCH | |
| SCHEMBL8944681 | 0.78 | MAPK1 (0.43) | NISCH | |
| SCHEMBL8944625 | 0.78 | NISCH (0.41) | NISCH | |
| SCHEMBL8944697 | 0.77 | HTR1B (0.49) | NISCH | |
| SCHEMBL8944556 | 0.76 | GAA (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638568-B1 | Substituted piperazines, their process of preparation and the pharmaceutical compositions containing them | ADIR (FR) | 1996-10-09 | — | — | EP | disclosed |
| US-5500426-A | ADMINISTERED TO IMPROVE GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-03-19 | — | — | US | disclosed |
| US-5492912-A | IMPROVES GLUCOSE TOLERANCE | ADIR ET COMPAGNIE (FR) | 1996-02-20 | — | — | US | disclosed |
| EP-0638568-A1 | Substituted piperazines, their process of preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-02-15 | — | — | EP | disclosed |