Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944957 | 0.88 | FAAH (0.41) | FAAHSCN4AL3MBTL1AOC3 | |
| SCHEMBL8945343 | 0.87 | FAAH (0.47) | FAAHMGLLHIF1ASCN4A | |
| SCHEMBL8945277 | 0.84 | KMT2A (0.40) | FAAHMGLLHIF1ASCN4AL3MBTL1 | |
| SCHEMBL8945137 | 0.84 | SCN4A (0.50) | FAAHMGLLSCN4ATACR1 | |
| SCHEMBL8945017 | 0.83 | FAAH (0.43) | FAAHMGLLSCN4A | |
| SCHEMBL8945218 | 0.77 | FAAH (0.44) | FAAHMGLLSCN4A | |
| SCHEMBL8945130 | 0.77 | FAAH (0.46) | FAAHMGLLMGAMGAASI | |
| SCHEMBL8945366 | 0.76 | FAAH (0.46) | FAAHMGLLHIF1ASCN4AL3MBTL1 | |
| SCHEMBL8945016 | 0.76 | FAAH (0.56) | FAAHMGLLSCN4AAOC3 | |
| SCHEMBL8945252 | 0.75 | SCN4A (0.51) | FAAHMGLLSCN4ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |