Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | SCN4A | P35499 | 6/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945002 | 0.86 | FAAH (0.42) | FAAHESR1ESR2SCN4AADRB1 | |
| SCHEMBL8945130 | 0.86 | FAAH (0.46) | FAAHMGLLESR1ESR2SCN4A | |
| SCHEMBL8945137 | 0.86 | SCN4A (0.50) | FAAHMGLLSCN4AACHEKCNH2 | |
| Hydrochloric Acid SCHEMBL8945257 | 0.85 | FAAH (0.41) | FAAHESR1ESR2SCN4AADRB1 | |
| SCHEMBL8944992 | 0.83 | FAAH (0.44) | FAAHMGLLSCN4A | |
| SCHEMBL8945277 | 0.82 | KMT2A (0.40) | FAAHMGLLSCN4AACHESSTR4 | |
| SCHEMBL8945218 | 0.79 | FAAH (0.44) | FAAHMGLLSCN4AACHESSTR4 | |
| SCHEMBL8945343 | 0.77 | FAAH (0.47) | FAAHMGLLESR2SCN4AACHE | |
| SCHEMBL8945366 | 0.76 | FAAH (0.46) | FAAHMGLLSCN4AACHESSTR4 | |
| SCHEMBL8945162 | 0.75 | FAAH (0.41) | FAAHMGLLSCN4AACHESSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |