Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802258 | 0.86 | HPGD (0.62) | NPSR1NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4141900 | 0.77 | PKM (0.76) | NPC1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4496604 | 0.77 | L3MBTL1 (0.76) | NPSR1NPC1LMNASMN1; SMN2ALDH1A1 | |
| Thiophanate SCHEMBL29398343 | 0.76 | ALDH1A1 (0.70) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| Thiophanate SCHEMBL20842 | 0.76 | ALDH1A1 (0.70) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11694452 | 0.75 | ALDH1A1 (0.79) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| Thiophanate SCHEMBL10922494 | 0.75 | ALDH1A1 (0.79) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| Thiophanate SCHEMBL7449541 | 0.75 | ALDH1A1 (0.68) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11834021 | 0.74 | ALDH1A1 (0.71) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4779529 | 0.74 | ALDH1A1 (0.60) | NPSR1NPC1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |