Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945165 | 0.77 | RAB9A (0.41) | ALDH1A1L3MBTL1NPC1RAB9AHTT | |
| SCHEMBL9536661 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL9535707 | 0.69 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL9536889 | 0.68 | LMNA (0.44) | ALDH1A1MAPTSMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL9535561 | 0.68 | LMNA (0.44) | ALDH1A1MAPTSMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL9534491 | 0.68 | LMNA (0.44) | ALDH1A1MAPTPKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL19079679 | 0.67 | PDE4D (0.70) | ALDH1A1MAPTPKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL9537059 | 0.66 | LMNA (0.47) | ALDH1A1SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL8945647 | 0.66 | ALDH1A1 (0.48) | ALDH1A1MAPTPKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL7495037 | 0.61 | LMNA (0.48) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |