Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945250 | 0.77 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1LMNAHPGD | |
| SCHEMBL9536661 | 0.73 | ALDH1A1 (0.44) | RAB9ANPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL9537059 | 0.71 | LMNA (0.47) | RAB9ANPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL9535707 | 0.69 | ALDH1A1 (0.48) | RAB9ANPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL9536889 | 0.68 | LMNA (0.44) | RAB9ANPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL9534491 | 0.68 | LMNA (0.44) | RAB9ANPC1ALDH1A1TP53LMNA | |
| SCHEMBL9535561 | 0.68 | LMNA (0.44) | RAB9ANPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL8945529 | 0.66 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1TP53LMNA | |
| SCHEMBL21589433 | 0.64 | PIK3C2A (0.61) | ALDH1A1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL4203830 | 0.63 | LMNA (0.60) | RAB9ANPC1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |