Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945334 | 0.89 | POLB (0.54) | ITGB3ITGA2BKMT2AS1PR1KDM4E | |
| SCHEMBL8842629 | 0.85 | LOXL2 (0.50) | KMT2AKDM4EHPGDLOXL2ALDH1A1 | |
| SCHEMBL19439177 | 0.84 | PARP1 (0.43) | ITGB3ITGA2BKDM4EHTTLOXL2 | |
| SCHEMBL29831137 | 0.79 | BRD4 (0.50) | KDM4EHPGDKDM5CKDM5BKDM4B | |
| SCHEMBL19439121 | 0.79 | BRD4 (0.50) | KDM4EHPGDKDM5CKDM5BKDM4B | |
| SCHEMBL28255647 | 0.78 | ITGB3 (0.74) | ITGB3ITGA2B | |
| SCHEMBL9561544 | 0.78 | POLB (0.51) | ITGB3ITGA2BKMT2AKDM4EPOLB | |
| SCHEMBL28292621 | 0.78 | BRAF (0.46) | KMT2AS1PR1KDM4ELOXL2ALDH1A1 | |
| SCHEMBL6613121 | 0.78 | MAP2K1 (0.44) | KMT2AS1PR1POLBHPGDHTT | |
| SCHEMBL13852609 | 0.78 | KMT2A (0.52) | KMT2AS1PR1POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641854-A | Integration stress access regulator | 卡里科生命科学有限责任公司 | 2019-04-16 | — | — | CN | disclosed |
| US-5519038-A | ENZYME INHIBITORS SUITABLE AS FIBROSUPPRESSANTS AND IMMUNOSUPPRESSANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |