Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.55 |
| ▸ | LAP3 | P28838 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | IL1RN | P18510 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945490 | 1.00 | LTA4H (0.55) | LTA4HLAP3RENMAOBIL1RN | |
| SCHEMBL7421085 | 0.94 | LTA4H (0.55) | LTA4HLAP3RENMAOBIL1RN | |
| SCHEMBL7425402 | 0.93 | LTA4H (0.48) | LTA4HLAP3RENMAOBIL1RN | |
| SCHEMBL7420013 | 0.92 | LTA4H (0.48) | LTA4HLAP3RENMAOBIL1RN | |
| SCHEMBL7414344 | 0.91 | LTA4H (0.49) | LTA4HLAP3RENMAOBIL1RN | |
| SCHEMBL8945580 | 0.91 | LTA4H (0.54) | LTA4HLAP3RENMAOBIL1RN | |
| SCHEMBL7418126 | 0.89 | LTA4H (0.53) | LTA4HLAP3RENMAOBLNPEP | |
| SCHEMBL8945614 | 0.85 | REN (0.47) | LTA4HRENMAOBPPARG | |
| SCHEMBL8945512 | 0.85 | REN (0.47) | LTA4HRENMAOBPPARG | |
| SCHEMBL8945246 | 0.82 | CTSD (0.53) | LTA4HREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559140-A | VIRICIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0565631-B1 | ANTI-VIRAL COMPOUNDS | MERRELL PHARMA INC (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0565631-A1 | ANTI-VIRAL COMPOUNDS. | MERRELL DOW PHARMA (US) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012123-A1 | ANTI-VIRAL COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-23 | — | — | WO | disclosed |