Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945490 | 0.92 | LTA4H (0.55) | LTA4HLAP3MAOBRENIL1RN | |
| SCHEMBL8945507 | 0.92 | LTA4H (0.55) | LTA4HLAP3MAOBRENIL1RN | |
| SCHEMBL7476893 | 0.91 | PGR (0.39) | LTA4HMAOBRENIL1RNERAP2 | |
| SCHEMBL7421085 | 0.88 | LTA4H (0.55) | LTA4HLAP3MAOBRENIL1RN | |
| SCHEMBL7425402 | 0.88 | LTA4H (0.48) | LTA4HLAP3MAOBRENIL1RN | |
| SCHEMBL7421310 | 0.87 | REN (0.49) | MAOBRENENPP2PPARA | |
| SCHEMBL7414344 | 0.85 | LTA4H (0.49) | LTA4HLAP3MAOBRENIL1RN | |
| SCHEMBL8945580 | 0.84 | LTA4H (0.54) | LTA4HLAP3MAOBRENIL1RN | |
| SCHEMBL8054257 | 0.84 | CTSD (0.48) | REN | |
| SCHEMBL7418126 | 0.81 | LTA4H (0.53) | LTA4HLAP3MAOBRENPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |