SCHEMBL8945699

SCHEMBL8945699

Nc1ccc(Oc2c(Cl)cc(Cl)cc2Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.59
MAOB P27338 1/20 0.59
ALDH1A1 P00352 7/20 0.52
TDP1 Q9NUW8 2/20 0.52
TSHR P16473 2/20 0.52
CYP3A4 P08684 1/20 0.52
SMN1; SMN2 Q16637 5/20 0.47
MAPT P10636 5/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MITF O75030 1/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
NLRP1 Q9C000 1/20 0.47
NOD2 Q9HC29 1/20 0.47
TEAD4 Q15561 1/20 0.43
PDE7A Q13946 2/20 0.42
POLB P06746 1/20 0.42
KDM1A O60341 1/20 0.42
CYP2C9 P11712 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8914412 0.88 MAOA (0.54) MAOAMAOBALDH1A1TDP1TSHR
SCHEMBL9683631 0.83 MAOA (0.59) MAOAMAOBALDH1A1TDP1TSHR
SCHEMBL9507276 0.83 MAOA (0.46) MAOAMAOBALDH1A1TDP1TSHR
SCHEMBL8914983 0.82 MAOA (0.53) MAOAMAOBALDH1A1TDP1TSHR
SCHEMBL8153815 0.82 MAOA (0.48) MAOAMAOBALDH1A1TDP1TSHR
SCHEMBL23061547 0.81 MAOA (0.56) MAOAMAOBALDH1A1TDP1TSHR
SCHEMBL8578409 0.80 THRB (0.49) MAOAMAOBALDH1A1TDP1TSHR
SCHEMBL11583376 0.80 MAOB (0.46) MAOAMAOBALDH1A1TDP1TSHR
SCHEMBL8151469 0.80 ALDH1A1 (0.50) MAOAMAOBALDH1A1TDP1TSHR
SCHEMBL8158114 0.80 NPBWR1 (0.46) MAOAMAOBALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4341326-A1 PROCESSES FOR MAKING POLYSILOXAZANES AND USING SAME FOR PRODUCING AMINO-FUNCTIONAL POLYORGANOSILOXANES Dow Silicones Corporation (US) 2024-03-27 EP claimed
WO-2022246363-A1 PROCESSES FOR MAKING POLYSILOXAZANES AND USING SAME FOR PRODUCING AMINO-FUNCTIONAL POLYORGANOSILOXANES DOW SILICONES CORPORATION (US) 2022-11-24 WO claimed
JP-8054391-A None JP disclosed
EP-4341326-A1 PROCESSES FOR MAKING POLYSILOXAZANES AND USING SAME FOR PRODUCING AMINO-FUNCTIONAL POLYORGANOSILOXANES Dow Silicones Corporation (US) 2024-03-27 EP disclosed
CN-110073474-B Zirconium precursor, hafnium precursor, titanium precursor and group 4-containing film deposited using the same 乔治洛德方法研究和开发液化空气有限公司 2023-09-01 CN disclosed
WO-2022246363-A1 PROCESSES FOR MAKING POLYSILOXAZANES AND USING SAME FOR PRODUCING AMINO-FUNCTIONAL POLYORGANOSILOXANES DOW SILICONES CORPORATION (US) 2022-11-24 WO disclosed
CN-114269762-A Novel group V and group VI transition metal precursors for thin film deposition 弗萨姆材料美国有限责任公司 2022-04-01 CN disclosed
JP-H0854391-A MONOCHRONAL ANTIBODY SPECIFIC TO DIPHENYLETHER COMPOUND, HYBRIDOMA, AND METHOD FOR DETECTING DIPHENYLETHER COMPOUND IATRON LAB INC 1996-02-27 JP disclosed