SCHEMBL9507276

SCHEMBL9507276

CC(C)(c1cc(Cl)cc(Cl)c1Oc1ccc(N)cc1)c1cc(Cl)cc(Cl)c1Oc1ccc(N)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.46
MAOB P27338 1/20 0.46
ALDH1A1 P00352 6/20 0.42
MAPT P10636 5/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
MAPK1 P28482 2/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 4/20 0.40
TDP1 Q9NUW8 3/20 0.39
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.39
TEAD4 Q15561 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
MITF O75030 1/20 0.37
GAA P10253 1/20 0.37
GFER P55789 1/20 0.37
NLRP1 Q9C000 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945699 0.83 MAOA (0.59) MAOAMAOBALDH1A1MAPTNPC1
SCHEMBL8151469 0.79 ALDH1A1 (0.50) MAOAMAOBALDH1A1MAPTNPC1
SCHEMBL8144916 0.75 ALDH1A1 (0.46) MAOAMAOBALDH1A1MAPTNPC1
SCHEMBL2947664 0.73 ALDH1A1 (0.53) MAOAMAOBALDH1A1MAPTNPC1
SCHEMBL8914412 0.72 MAOA (0.54) MAOAMAOBALDH1A1MAPTNPC1
SCHEMBL11583376 0.69 MAOB (0.46) MAOAMAOBALDH1A1MAPTNPC1
SCHEMBL11720872 0.69 RAB9A (0.59) MAOAMAOBALDH1A1MAPTNPC1
SCHEMBL8158114 0.69 NPBWR1 (0.46) MAOAMAOBALDH1A1MAPTNPC1
SCHEMBL8578409 0.69 THRB (0.49) MAOAMAOBALDH1A1MAPTNPC1
SCHEMBL9683631 0.69 MAOA (0.59) MAOAMAOBALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0200204-B1 MELT-FUSIBLE COPOLYIMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-01 EP claimed
EP-0200204-A2 Melt-fusible copolyimides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-11-05 EP claimed
EP-0200204-B1 MELT-FUSIBLE COPOLYIMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-01 EP disclosed
US-4725642-A USING AN ETHER- OR THIOETHER-CONTAINING AROMATIC DIAMINE; AIRCRAFT PANELS; PRINTED CIRCUITS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-02-16 US disclosed
EP-0200204-A2 Melt-fusible copolyimides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-11-05 EP disclosed