Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718482 | 0.87 | NPSR1 (0.44) | NPSR1ALDH1A1KMT2AKDM4EP2RX7 | |
| SCHEMBL28268679 | 0.84 | ALDH1A1 (0.56) | NPSR1ALDH1A1KMT2AKDM4EP2RX7 | |
| SCHEMBL3475461 | 0.81 | NPSR1 (0.47) | NPSR1ALDH1A1KMT2AKDM4ENPC1 | |
| SCHEMBL4474250 | 0.81 | TBXAS1 (0.38) | NPSR1ALDH1A1KMT2AP2RX7NPC1 | |
| SCHEMBL27616306 | 0.80 | NPSR1 (0.38) | NPSR1ALDH1A1KMT2AKDM4ENPC1 | |
| SCHEMBL16964280 | 0.80 | KMT2A (0.41) | NPSR1KMT2AKDM4EP2RX7HTT | |
| SCHEMBL5474563 | 0.79 | NPSR1 (0.50) | NPSR1ALDH1A1KMT2AKDM4ENPC1 | |
| SCHEMBL2538190 | 0.78 | NPSR1 (0.45) | NPSR1ALDH1A1KMT2AKDM4ENPC1 | |
| SCHEMBL4592999 | 0.77 | P2RX7 (0.40) | NPSR1ALDH1A1KMT2AKDM4EP2RX7 | |
| SCHEMBL11963737 | 0.77 | KMT2A (0.37) | NPSR1ALDH1A1KMT2AKDM4EP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |