Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | PIM1 | P11309 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.68 |
| ▸ | FLT3 | P36888 | 1/20 | 0.68 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.68 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460969 | 0.82 | LMNA (0.51) | NPC1RAB9ASMN1; SMN2PIM1ADORA3 | |
| SCHEMBL9317689 | 0.81 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2PIM1ADORA3 | |
| SCHEMBL305498 | 0.80 | TAAR1 (1.00) | NPC1RAB9ASMN1; SMN2PIM1ADORA3 | |
| SCHEMBL17664185 | 0.79 | KDR (0.67) | NPC1RAB9ALMNATP53KMT2A | |
| SCHEMBL5264810 | 0.78 | CHRNB2 (0.55) | NPC1RAB9ATAAR1LMNAEPHX2 | |
| SCHEMBL8807003 | 0.78 | CHRNB2 (0.64) | NPC1RAB9ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL28755924 | 0.77 | EPHX2 (0.54) | SMN1; SMN2LMNAEPHX2CHRNB2CHRNB4 | |
| SCHEMBL14517928 | 0.77 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2PIM1ADORA3 | |
| SCHEMBL6906687 | 0.76 | ROCK2 (0.60) | NPC1RAB9ASMN1; SMN2EPHX1CHRNB2 | |
| SCHEMBL6906691 | 0.76 | HTT (0.51) | NPC1RAB9ASMN1; SMN2CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0052668-B1 | N-(4-PYRIDAZINYL)-N'-PHENYLUREAS AND -THIOUREAS AS WELL AS PLANT GROWTH REGULATORS CONTAINING SAME | Shudo, Koichi, Prof. Dr. (JP) | 1984-03-14 | — | — | EP | disclosed |
| US-4397678-A | ACCELERATION AND SUPPRESSION | Okamoto, Toshihiko (JP) | 1983-08-09 | — | — | US | disclosed |
| US-4331807-A | Pyridazine urea plant growth regulators | Okamoto, Toshihiko (JP) | 1982-05-25 | — | — | US | disclosed |
| US-4053475-A | ANTI-ALLERGIC AGENTS | STERLING DRUG INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4008235-A | ANTIALLERGIC | STERLING DRUG INC. (US) | 1977-02-15 | — | — | US | disclosed |