Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946617 | 0.92 | L3MBTL1 (0.53) | L3MBTL1NTRK1PYGLNTRK3NTRK2 | |
| SCHEMBL8946735 | 0.90 | L3MBTL1 (0.51) | L3MBTL1NTRK1RAB9ADHODHNTRK3 | |
| SCHEMBL8946595 | 0.85 | L3MBTL1 (0.50) | L3MBTL1NTRK1HTTMEN1RAB9A | |
| SCHEMBL8946420 | 0.84 | L3MBTL1 (0.47) | L3MBTL1NTRK1PYGLNTRK3NTRK2 | |
| SCHEMBL8946710 | 0.84 | HTT (0.47) | L3MBTL1HTTMEN1RAB9AKMT2A | |
| SCHEMBL8946885 | 0.84 | DHODH (0.49) | L3MBTL1NTRK1DHODH | |
| SCHEMBL8946654 | 0.84 | L3MBTL1 (0.55) | L3MBTL1NTRK1HTTMEN1RAB9A | |
| SCHEMBL8946750 | 0.84 | L3MBTL1 (0.48) | L3MBTL1NTRK1HTTMEN1KMT2A | |
| SCHEMBL8946576 | 0.84 | L3MBTL1 (0.51) | L3MBTL1NTRK1KMT2ACYP2C9NTRK3 | |
| SCHEMBL8946618 | 0.84 | L3MBTL1 (0.51) | L3MBTL1NTRK1KMT2ACYP2C9NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |