Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946700 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL8946693 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL9844767 | 0.74 | MTNR1A (0.39) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL9844777 | 0.74 | MTNR1A (0.39) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL9844773 | 0.74 | MTNR1A (0.39) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL277613 | 0.73 | MAPT (0.50) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL8946291 | 0.73 | MAPT (0.50) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL8946294 | 0.73 | MAPT (0.50) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL8946628 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL8946623 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |