SCHEMBL8946782

SCHEMBL8946782

C=C(CCCC)C(=O)NC(O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.38
PLA2G5 P39877 3/20 0.38
FAAH O00519 2/20 0.36
GPR84 Q9NQS5 3/20 0.36
FFAR1 O14842 2/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
NOD1 Q9Y239 1/20 0.35
MAPK1 P28482 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TGFBR1 P36897 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
AKR1B1 P15121 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CA2 P00918 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2532099 0.81 TGFBR1 (0.37) TGFBR1
SCHEMBL8946793 0.76 PLA2G2A (0.34) PLA2G2APLA2G5FAAHCES2CES1
SCHEMBL29702819 0.73 MEN1 (0.61) PLA2G2APLA2G5FAAHCES2CES1
SCHEMBL8089101 0.72 HSP90AA1 (0.45) GPR84CES2CES1MEN1KMT2A
SCHEMBL325418 0.72 CES1 (0.44) GPR84FFAR1CES2CES1MEN1
SCHEMBL28890853 0.71 FAAH (0.47) PLA2G2AFAAHCES2CES1KMT2A
SCHEMBL29872685 0.71 CES1 (0.42) GPR84FFAR1CES2CES1MEN1
SCHEMBL28165600 0.71 CES1 (0.42) FAAHGPR84CES2CES1MEN1
SCHEMBL28394299 0.70 FAAH (0.63) FAAHGPR84NOD1MAPK1MEN1
SCHEMBL28401281 0.70 FAAH (0.63) FAAHGPR84NOD1MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5496896-A Curable composition based on a Michael addition product, processes for its preparation and its use BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1996-03-05 US claimed
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US claimed
EP-0361048-B1 CURABLE COMPOSITION CONTAINING A MICHAEL ADDITION PRODUCT, ITS PREPARATION AND ITS USE BASF Lacke + Farben AG (DE) 1993-05-26 EP claimed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US claimed
EP-0287842-B1 CURABLE COMPOSITIONS CONTAINING A MICHAEL-ADDITION PRODUCT, THEIR PREPARATION AND USE BASF Lacke + Farben AG (DE) 1991-06-12 EP claimed
US-4808660-A LOW TEMPERATURE CURABLE, TENSILE STRENGTH GENCORP INC. (US) 1989-02-28 US claimed
US-5496896-A Curable composition based on a Michael addition product, processes for its preparation and its use BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1996-03-05 US disclosed
US-5300571-A Hardenable composition based on a Michael addition product, process for its preparation and its use BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1994-04-05 US disclosed
EP-0020000-A1 Activated ester monomers, polymers formed therefrom and coating compositions containing said polymers AMERICAN CYANAMID COMPANY (US) 1980-12-10 EP disclosed