SCHEMBL8946793

SCHEMBL8946793

C=C(CCCC)C(=O)NC(OCCCC)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.34
PLA2G5 P39877 3/20 0.34
PPARG P37231 2/20 0.33
PPARA Q07869 1/20 0.33
TLR2 O60603 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NOD1 Q9Y239 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PLA2G2C Q5R387 1/20 0.31
DDAH1 O94760 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
FAAH O00519 2/20 0.30
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5012516 0.79 PPARG (0.38) PPARGPPARATSHRALDH1A1MAPK1
SCHEMBL8946782 0.76 PLA2G2A (0.38) PLA2G2APLA2G5NPSR1NOD1ALDH1A1
SCHEMBL10876493 0.72 TGFBR1 (0.33)
SCHEMBL9316631 0.71 TSHR (0.44) HPGDTSHRALDH1A1MAPK1
SCHEMBL8503701 0.68 ALDH1A1 (0.34) HPGDTSHRALDH1A1
SCHEMBL144390 0.67 TGFBR1 (0.34)
SCHEMBL9515219 0.67 TGFBR1 (0.50) TSHRALDH1A1
SCHEMBL29702819 0.67 MEN1 (0.61) PLA2G2APLA2G5CES2CES1FAAH
SCHEMBL8089101 0.67 HSP90AA1 (0.45) PPARGPPARATLR2TSHRALDH1A1
SCHEMBL325418 0.67 CES1 (0.44) PPARGPPARATLR2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5496896-A Curable composition based on a Michael addition product, processes for its preparation and its use BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1996-03-05 US claimed
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US claimed
EP-0361048-B1 CURABLE COMPOSITION CONTAINING A MICHAEL ADDITION PRODUCT, ITS PREPARATION AND ITS USE BASF Lacke + Farben AG (DE) 1993-05-26 EP claimed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US claimed
EP-0049910-B1 COPOLYMERS FORMED FROM ACTIVATED ESTER MONOMERS, AND COATING COMPOSITIONS CONTAINING SAID COPOLYMERS AMERICAN CYANAMID COMPANY (US) 1986-02-19 EP claimed
US-5496896-A Curable composition based on a Michael addition product, processes for its preparation and its use BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1996-03-05 US disclosed
US-5300571-A Hardenable composition based on a Michael addition product, process for its preparation and its use BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1994-04-05 US disclosed
US-5227432-A BRANCHED ACRYLATE COPOLYMER WITH POLYMERIZABLE DOUBLE BONDS AND METHODS FOR THE PRODUCTION OF THE ACRYLATE COPOLYMER BASF LACKE & FARBEN AG (DE) 1993-07-13 US disclosed
US-4760168-A Preparation of alkyl acrylamidoglycolates and their alkyl ethers AMERICAN CYANAMID COMPANY (US) 1988-07-26 US disclosed