SCHEMBL8946784

SCHEMBL8946784

C=CC(=O)N(CCCC)C(O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.40
ZDHHC2 Q9UIJ5 2/20 0.40
GPR84 Q9NQS5 3/20 0.35
FFAR1 O14842 1/20 0.35
TSHR P16473 2/20 0.34
HPGD P15428 1/20 0.34
ALDH1A1 P00352 1/20 0.33
EPHX2 P34913 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
CA2 P00918 1/20 0.32
MAPK1 P28482 1/20 0.32
FAAH O00519 1/20 0.31
MAPT P10636 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP8 P22894 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8946934 0.91 ZDHHC20 (0.44) ZDHHC20ZDHHC2GPR84FFAR1TSHR
SCHEMBL28032429 0.82 ZDHHC20 (0.41) ZDHHC20ZDHHC2TSHRHPGDALDH1A1
SCHEMBL2532101 0.82 ALDH1A1 (0.33) ZDHHC20ZDHHC2TSHRALDH1A1
SCHEMBL799415 0.77 ZDHHC20 (0.41) ZDHHC20ZDHHC2TSHRHPGDALDH1A1
SCHEMBL9285153 0.76 OR51E2 (0.31)
Ether SCHEMBL11039292 0.75 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL7212046 0.74 LMNA (0.35) ALDH1A1
SCHEMBL28073684 0.74 ZDHHC20 (0.51) ZDHHC20ZDHHC2TSHRHPGDALDH1A1
SCHEMBL15280053 0.73 MMP1 (0.40) ZDHHC20ZDHHC2TSHRHPGDMMP1
SCHEMBL10477081 0.72 TSHR (0.46) ZDHHC20ZDHHC2TSHRHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5496896-A Curable composition based on a Michael addition product, processes for its preparation and its use BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1996-03-05 US claimed
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US claimed
EP-0361048-B1 CURABLE COMPOSITION CONTAINING A MICHAEL ADDITION PRODUCT, ITS PREPARATION AND ITS USE BASF Lacke + Farben AG (DE) 1993-05-26 EP claimed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US claimed
EP-0287842-B1 CURABLE COMPOSITIONS CONTAINING A MICHAEL-ADDITION PRODUCT, THEIR PREPARATION AND USE BASF Lacke + Farben AG (DE) 1991-06-12 EP claimed
US-4808660-A LOW TEMPERATURE CURABLE, TENSILE STRENGTH GENCORP INC. (US) 1989-02-28 US claimed
US-5496896-A Curable composition based on a Michael addition product, processes for its preparation and its use BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1996-03-05 US disclosed
US-5300571-A Hardenable composition based on a Michael addition product, process for its preparation and its use BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1994-04-05 US disclosed