SCHEMBL8946785

SCHEMBL8946785

CCCCC=CC(=O)NC(O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.49
TAS1R1 Q7RTX1 1/20 0.49
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41
FAAH O00519 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SLC6A5 Q9Y345 1/20 0.40
PSMB11 A5LHX3 1/20 0.39
PSMA7 O14818 1/20 0.39
PSMB1 P20618 1/20 0.39
PSMA1 P25786 1/20 0.39
PSMA2 P25787 1/20 0.39
PSMA3 P25788 1/20 0.39
PSMA4 P25789 1/20 0.39
PSMB8 P28062 1/20 0.39
PSMB9 P28065 1/20 0.39
PSMA5 P28066 1/20 0.39
PSMB4 P28070 1/20 0.39
PSMB6 P28072 1/20 0.39
PSMB5 P28074 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8946936 0.91 TAS1R3 (0.42) TAS1R3TAS1R1F7F3FAAH
SCHEMBL2532104 0.82 TAS1R3 (0.42) TAS1R3TAS1R1PPARGPPARAALDH1A1
SCHEMBL29499016 0.80 TAS1R3 (0.53) TAS1R3TAS1R1FAAHPSMB11PSMA7
SCHEMBL17559259 0.78 PLA2G2A (0.51) TAS1R3TAS1R1CNR1CNR2ALDH1A1
SCHEMBL17559257 0.78 PLA2G2A (0.51) TAS1R3TAS1R1CNR1CNR2ALDH1A1
SCHEMBL2190885 0.77 FAAH (0.62) TAS1R3TAS1R1FAAHSMN1; SMN2SLC6A5
SCHEMBL10951078 0.77 FAAH (0.62) TAS1R3TAS1R1FAAHSMN1; SMN2SLC6A5
SCHEMBL10956216 0.77 FAAH (0.62) TAS1R3TAS1R1FAAHSMN1; SMN2SLC6A5
SCHEMBL18796614 0.76 FAAH (0.48) TAS1R3TAS1R1FAAHSMN1; SMN2SLC6A5
SCHEMBL18796616 0.76 FAAH (0.48) TAS1R3TAS1R1FAAHSMN1; SMN2SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5496896-A Curable composition based on a Michael addition product, processes for its preparation and its use BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1996-03-05 US claimed
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US claimed
EP-0361048-B1 CURABLE COMPOSITION CONTAINING A MICHAEL ADDITION PRODUCT, ITS PREPARATION AND ITS USE BASF Lacke + Farben AG (DE) 1993-05-26 EP claimed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US claimed
EP-0287842-B1 CURABLE COMPOSITIONS CONTAINING A MICHAEL-ADDITION PRODUCT, THEIR PREPARATION AND USE BASF Lacke + Farben AG (DE) 1991-06-12 EP claimed
US-4808660-A LOW TEMPERATURE CURABLE, TENSILE STRENGTH GENCORP INC. (US) 1989-02-28 US claimed
US-5496896-A Curable composition based on a Michael addition product, processes for its preparation and its use BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1996-03-05 US disclosed
US-5300571-A Hardenable composition based on a Michael addition product, process for its preparation and its use BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1994-04-05 US disclosed