Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KMO | O15229 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28762430 | 0.82 | MAPT (0.45) | ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL8947158 | 0.78 | ADORA3 (0.53) | ALDH1A1SMN1; SMN2KDM4EMAPTADORA2A | |
| SCHEMBL28402665 | 0.78 | HSD17B1 (0.53) | ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL2638150 | 0.78 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2KMOKMT2AMEN1 | |
| SCHEMBL8842864 | 0.73 | KMO (0.56) | ALDH1A1SMN1; SMN2KMOKMT2AMEN1 | |
| SCHEMBL979633 | 0.73 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2KMOKMT2AMEN1 | |
| SCHEMBL1199183 | 0.73 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2KMOKMT2AMEN1 | |
| SCHEMBL23794594 | 0.72 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMOKMT2AMEN1 | |
| SCHEMBL8843382 | 0.71 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMOKMT2AMEN1 | |
| SCHEMBL11002986 | 0.71 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMOKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583092-A | PLANT ANTIGROWTH AGENTS | AMERICAN CYANAMID COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0726261-A1 | Herbidical 1,2,4 thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0726260-A1 | Herbicidal (1,2,4)thiadiazoles | AMERICAN CYANAMID COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |