Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711268 | 0.85 | ADORA3 (0.55) | ADORA3ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL8947225 | 0.84 | SMN1; SMN2 (0.50) | KDM4ESMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL8340158 | 0.84 | ADORA3 (0.54) | ADORA3ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL28762430 | 0.80 | MAPT (0.45) | KDM4ESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8947147 | 0.79 | NPC1 (0.43) | KDM4ESMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL8947041 | 0.78 | ALDH1A1 (0.57) | ADORA2AADORA1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL11643375 | 0.77 | TRPM8 (0.57) | ADORA3KDM4ETP53HSD17B10SMN1; SMN2 | |
| SCHEMBL892711 | 0.74 | HDAC1 (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9029245 | 0.74 | ALDH1A1 (0.46) | KDM4ETP53HSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL8101030 | 0.74 | ADORA3 (0.59) | ADORA3ADORA2AADORA2BADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583092-A | PLANT ANTIGROWTH AGENTS | AMERICAN CYANAMID COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| CN-1134936-A | Herbicidal (1,2,4) thiadiazoles | AMERICAN CYANAMID CO (US) | 1996-11-06 | — | — | CN | disclosed |
| EP-0726261-A1 | Herbidical 1,2,4 thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0726260-A1 | Herbicidal (1,2,4)thiadiazoles | AMERICAN CYANAMID COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |