Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | BLVRB | P30043 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947158 | 0.79 | ADORA3 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8947225 | 0.75 | SMN1; SMN2 (0.50) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2693403 | 0.75 | ACHE (0.63) | KDM4EALDH1A1LDHAHDAC6EIF4E | |
| SCHEMBL8947253 | 0.72 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2PKMHPGD | |
| SCHEMBL8840310 | 0.71 | KDM4E (0.54) | NPC1RAB9ARXFP1KDM4ESMN1; SMN2 | |
| SCHEMBL4606363 | 0.70 | PTGS2 (0.42) | KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9029245 | 0.69 | ALDH1A1 (0.46) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL27782182 | 0.69 | KMO (0.68) | NPC1RAB9A | |
| SCHEMBL8605221 | 0.69 | PLK4 (0.43) | NPC1RAB9AACMSDDHODH | |
| SCHEMBL4603390 | 0.68 | TSHR (0.42) | NPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583092-A | PLANT ANTIGROWTH AGENTS | AMERICAN CYANAMID COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| CN-1134936-A | Herbicidal (1,2,4) thiadiazoles | AMERICAN CYANAMID CO (US) | 1996-11-06 | — | — | CN | disclosed |
| EP-0726261-A1 | Herbidical 1,2,4 thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0726260-A1 | Herbicidal (1,2,4)thiadiazoles | AMERICAN CYANAMID COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |