Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17960860 | 0.82 | ADORA3 (0.54) | SMN1; SMN2 | |
| SCHEMBL27508760 | 0.82 | CYP19A1 (0.48) | HSD17B1HSD17B2SMN1; SMN2AURKACSNK2A1 | |
| SCHEMBL8947213 | 0.81 | LMNA (0.49) | SMN1; SMN2FAAHNR4A2 | |
| SCHEMBL20501753 | 0.77 | TP53 (0.51) | SMN1; SMN2CSNK2A1GRK6 | |
| SCHEMBL8947073 | 0.76 | TTR (0.46) | KDM4EFAAHDHODHPIM1 | |
| SCHEMBL27651907 | 0.74 | KIF11 (0.49) | KMO | |
| SCHEMBL8803518 | 0.74 | KDM4E (0.42) | PIN1HSD17B1HSD17B2KDM4EESR2 | |
| SCHEMBL3769512 | 0.74 | KDM4E (0.42) | HSD17B1HSD17B2KDM4EFAAH | |
| SCHEMBL13002810 | 0.74 | MGAM (0.44) | HSD17B1HSD17B2TRPM8KDM4EFAAH | |
| SCHEMBL19195986 | 0.74 | HSD17B1 (0.54) | HSD17B1HSD17B2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583092-A | PLANT ANTIGROWTH AGENTS | AMERICAN CYANAMID COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| CN-1134936-A | Herbicidal (1,2,4) thiadiazoles | AMERICAN CYANAMID CO (US) | 1996-11-06 | — | — | CN | disclosed |
| EP-0726260-A1 | Herbicidal (1,2,4)thiadiazoles | AMERICAN CYANAMID COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0726261-A1 | Herbidical 1,2,4 thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |